Pharmaceutical Anastrozole Arimidex Anti Estrogen Steroid Hormone
|Product name||Anastrozole, Arimidex, Breast Cancer Treatment Drugs|
|Appearance:||an off-white color crystalline powder|
|Product Categories||Active Pharmaceutical Ingredients;Antineoplastic;All
Inhibitors;anti-neoplastic;Inhibitors;Intermediates & Fine
Anastrozole Usage :
1) It is the third-generation’s aromatase inhibitors, used for the
treatment of advanced breast cancer of postmenopausal patients.
(2) Its used to cure the breast cancer.
(3) Anastrozole is the third-generation’s aromatase inhibitors,
used for the treatment of advanced breast cancer of postmenopausal
patients. It is an inhibitor for the triazole aromatase with a
strong selectivity. It can inhibits aromatase which is prerequisite
for the synthesis of pigment cells P-450 thereby blocking the
biosynthesis of estrogens, and the estrogen is the essential part
of the growth of breast cancer cells. Its used to cure the breast
cancer, particularly suitable for postmenopausal women with
advanced breast cancer who recrudescent after hormone adjuvant
This medication is used to treat breast cancer in women who have
gone through "the change of life" (menopause). Anastrozole works by
lowering estrogen hormone levels to help shrink tumors and slow
Usual Adult Dose for Breast Cancer
Initial dose: 1 mg orally taken once a day
Duration of therapy: Until tumor progression (treatment of advanced
breast cancer); unknown (adjuvant treatment of early breast cancer)
----Adjuvant treatment of postmenopausal women with hormone
receptor-positive early breast cancer;
-----First-line treatment of postmenopausal women with hormone
receptor-positive or hormone receptor unknown locally advanced or
metastatic breast cancer;
-----Second-line treatment of advanced breast cancer in
postmenopausal women with disease progression following tamoxifen
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
Mild to Moderate Hepatic Impairment: No adjustment recommended.
Stable Hepatic Cirrhosis: No adjustment recommended.
Severe Hepatic Impairment: Data not available.
How to use Anastrozole
Take this medication by mouth with or without food, usually once a
day, or as directed by your doctor.
Use this medication regularly in order to get the most benefit from
it. Remember to use it at the same time each day.
Do not increase your dose or take this medication more often
without your doctor's approval. Your condition will not improve any
faster and the risk of serious side effects may be increased.
Since this drug can be absorbed through the skin, women who are
pregnant or who may become pregnant should not handle or break the
tablets of this medication.
Your healthcare professionals (e.g., doctor or pharmacist) may
already be aware of any possible drug interactions and may be
monitoring you for it. Do not start, stop, or change the dosage of
any medicine before checking with them first.
This drug should not be used with the following medications because
very serious interactions may occur: estrogens, tamoxifen.
If you are currently using any of these medications listed above,
tell your doctor or pharmacist before starting anastrozole.
Before using this medication, tell your doctor or pharmacist of all
prescription and nonprescription/herbal products you may use.
The COA of Anastrozole (arimidex):
|Description||White crystalline powder||Complies|
|Conform with standard IR|
Conform with standard HPLC
|Solubility||Freely soluble in methanol, acetone, ethanol and tetrahydrofuran.
And very soluble in acetonitrile||Complies|
|Total Unspecified Impurity||max. 0.2%||0.08%|
|Individual unspecified impurlty||max. 0.1%||0.05%|
|Related compound B||max. 0.2%||0.07%|
|Related compound C||max. 0.2%||0.04%|
|Related compound D||max. 0.1%||0.05%|
|Related compound E||max. 0.1%||0.06%|
|Limit of cyclohexane||max. 0.08%||ND|
|Limit of ethylacetate||max. 0.1%||0.07%|
|Residue on ignition||max. 0.1%||0.07%|
|Storage||Cool and dry|
|Conclusion||It complies to USP32 .|
|Letrozole Femara||CAS 112809-51-5|
|Tamoxifen Citrate Novadex||CAS 54965-24-1|
|Clomifene citrate Serophene||CAS 50-41-9|
|Anastrozole Arimidex||CAS 120511-73-1|
|Exemestane Aromasin||CAS 107868-30-4|
Packaging & Delivery
1. Sufficient stock, so delivery promptly very day is OK after
receive the payment.
2. Well-trained and disciplined packing team:provide unique&
safe ways to ship 10g-100kg powers at one time to customers
3. Professional logistic agent We make sure of fast delivery and
4. Packing pictures and tacking code are provided within 24 hours
after receiving the payment.Updated tracking information will be
provided every other day.