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Albuterol Sulfate CAS 51022-70-9 Bronchial Asthma White Powder All Inhibitors

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Albuterol Sulfate CAS 51022-70-9 Bronchial Asthma White Powder All Inhibitors

Brand Name : Jusheng Brand
Model Number : 51022-70-9
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 1 liter, 10 litrers
CAS : 51022-70-9
Alias : Albuterol Sulfate
Apparence : White Crystalline Solid
Packing : 1KG, 10KG , 25KG
Stock : Enough Stock
Usage : for Bronchial Asthma
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Albuterol Sulfate CAS 51022-70-9 Bronchial Asthma White Powder All Inhibitors


Quick detail


Name:Albuterol sulfate
CAS No.:51022-70-9
Formula:2(C13H21NO3).H2O4S
Molecular Weight:576.70
Synonyms:.alpha.1-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-.alpha., .alpha.-diol sulfate (2:1) salt;Bronchospray;(+-)-Salbutamol sulfate;Albuterol sulfate (USP);1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylamino)ethanol sulfate;Loftan;Epaq;1,3-Benzenedimethanol, alpha1-(((1,1-dimethylethyl)amino)methyl)-4-hydroxy-, sulfate (2:1) (salt) (9CI);Ventolin HFA;Emican;Salbutamol hemisulfate;Broncho Inhalat;Huma-Salmol;Albuterol sulfate / Salbutamol sulfate;
EINECS:256-916-8
Melting Point:180 °C
Boiling Point:433.5 °C at 760 mmHg
Flash Point:159.5 °C
Solubility:soluble in water
Appearance:white crystalline solid

Albuterol Sulfate Description


Albuterol Sulfate/Salbutamol/Ventolin powders/Proventil powders/CAS No: 51022-70-9

It is usually given by the inhaled route for direct effect on bronchial smooth muscle. This is usually achieved through a metered dose inhaler (MDI), nebulizer or other proprietary delivery devices (e.g. Rotahaler or Autohaler). In these forms of delivery, the maximal effect of salbutamol can take place within five to 20 minutes of dosing, though some relief is immediately seen. It can also be given intravenously.

Used in the treatment of bronchial asthma, asthmatic bronchitis, emphysema, patients bronchospasm.


Albuterol Sulfate DOSAGE AND ADMINISTRATION


For treatment of acute episodes of bronchospasm or prevention of asthmatic symptoms, the usual dosage for adults and children 4 years of age and older is two inhalations repeated every 4 to 6 hours. More frequent administration or a larger number of inhalations is not recommended. In some patients, one inhalation every 4 hours may be sufficient.


Each actuation of PROVENTIL® HFA Inhalation Aerosol delivers 108 mcg of albuterol sulfate (equivalent to 90 mcg of albuterol base) from the mouthpiece. It is recommended to prime the inhaler before using for the first time and in cases where the inhaler has not been used for more than 2 weeks by releasing four “test sprays” into the air, away from the face.


Possible Side Effects of Albuterol Sulfate


Call your doctor at once if you have a serious side effect such as:

  • bronchospasm (wheezing, chest tightness, trouble breathing), especially after starting a new canister of this medicine;
  • chest pain and fast, pounding, or uneven heart beats;
  • tremor, nervousness;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp...

Specifications:


Test ItemsSpecificationTest Results
Appearancewhite oralmost white,crystalline powderConform
SolubilityFreely soluble in water,practically insoluble or very slightly soluble in alcohol and in methylene chloride.Conform
IdentificationAThe UV absorption spectrum of the sample shows an absorption maximum at 276nm.The specific absorbance at the Maximum is55 to 64.Conform
BInfraed absorption spectrophotometry.Conform
CChromatogram obtained with test solution (b) is similar in position color & size to the principal spot in the chromatogram obtained with the reference solution.Conform
DAn orange-red color develop in methylene chloride layer.Conform
EIt geves reaction (a) of sulphates.Conform
Appearance of solutionSolution S is clear and not more intensely coloured than reference solution in BY6.Conform
Optical rotation﹣0.10° to +0.10°determined on solution S.+0.01°
Acidity or alkalinityNMT 0.4ml of 0.01M HCL is required to change the color of the indicator to red.Conform
Related substancesImpurity J ≤0.20%Conform
Any other impurity ≤0.30%Conform
Total impurity ≤1.0%Conform
Boron≤50ppmConform
Sulphated ash≤0.10%0.06%
Loss on drying≤0.5%0.30%
Assay(on dried basis)98.0~101.0%98.8%
Conclusion

The test results above BP2009


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