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Wuhan Senwayer Century Chemical Co., Ltd.
Wuhan Senwayer Century Chemical Co., Ltd.
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6 Years

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Rosiglitazone White Crystalline Powder Maleate Pharma Antidiabetic Raw Powders

Wuhan Senwayer Century Chemical Co., Ltd.

City: wuhan

Province/State:hubei

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Rosiglitazone White Crystalline Powder Maleate Pharma Antidiabetic Raw Powders

Brand Name : Senwayer Brand

Model Number : 155141-29-0

Certification : ISO, 9001, USP

Place of Origin : China

MOQ : 10grams

Price : Discount is possible if your order is big enough

Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.

Supply Ability : 1000kg/month

Delivery Time : within 2 working days

Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg

Stock : Enough Stock

Packing : As your requirement

CAS : 122320-73-4

Apparence : Almost White Crystalline Powder

Purity : 99%

Usage : Antidiabetic Raw Powders

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Rosiglitazone Maleate CAS 122320-73-4 Maleate Pharma Antidiabetic Raw Powders

Quick detail


Product name: Rosiglitazone

Synonyms: 5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;AVANDIA;ROSIGLITAZONE;ROSIGLITAZONE HCL;Rosiglitazone free base;Rosiglitazone and its intermediates;ROSIGLITAZONE 99%

CAS: 122320-73-4

MF: C18H19N3O3S

MW: 357.43

Key Word: Rosiglitazone, Rosiglitazone Hcl, Rosiglitazone base, AVANDIA,

Description


Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride.

Application


Rosiglitazone was approved by the US FDA in 1999 and by the EMEA in 2000; the EMEA however required two postmarketing studies on longterm adverse effects, one for chronic heart failure and the other for cardiovascular effects. The drug was approved for glycemic control in people with type 2 diabetes, as measured by glycosylated haemoglobin A1c (HbA1c) as a surrogate endpoint, similar to that of other oral antidiabetic drugs. The controversy over adverse effects has dramatically reduced the use of rosiglitazone.

Properties
Appearance: White to off-white crystalline powder
Density: 1.315g/cm3
Melting Point: 153-155ºC
Boiling Point: 585ºC at 760mmHg
Flash Point: 307.6ºC
Vapor Pressure: 1.14E-13mmHg at 25°C

Usage


Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR- γ)
Thiazole alkanes antidiabetic drug

Research


Rosiglitazone was thought to be able to benefit patients with Alzheimer's disease who do not express the ApoE4 allele, but the phase III trial designed to test this showed that rosiglitazone was ineffective in all patients, including ApoE4-negative patients.


Rosiglitazone may also treat mild to moderate ulcerative colitis, due to its anti-inflammatory properties as a PPAR ligand.

Order infos


Payment Methods:West Union,Moeny Gram, Bitcoin and Bank Transfer.
Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
Shipment Time:Within 12 hours after confirmation of your payment
Other Service:Safe shipment,high purity and best price for you.

Rosiglitazone White Crystalline Powder Maleate Pharma Antidiabetic Raw Powders


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